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Using dexmeditomidine with midazolam and ketamine, as premedication in children of age group 3-10 years, and comapring their effects.

A comparative evaluation of nebulized dexmedetomidine-ketamine versus nebulized dexmedetomidine-midazolam as premedication in pediatric patients undergoing surgery under general anesthesia:A prospective, randomized double blind study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/05/013772
Enrollment
60
Registered
2018-05-08
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients of age group 3-10 years,undergoing elective surgery under general anesthesia, having ASA 1 & 2

Interventions

Intervention1: Nebulization: Nebulization will be done in pediatric patients 30 minutes prior to surgical procedure. Control Intervention1: Ketamine: Ketamine 0.5 mcg/kg with Dexmedetomidine 1 mcg/kg

Sponsors

Dr RPGMC Kangra atTanda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA Class I & II. 2.Weight between 8-40 kgs. 3.Undergoing elective surgical procedure.

Exclusion criteria

Exclusion criteria: 1.Known allergy to the study drug. 2.Organ dysfunction. 3.Cardiac dysrrhythmia and/or Congenital heart disease. 4.Psychotropic medication use and mental retardation. 5.History of chronic illness,prematurity,or developmental delay. 6.Medical conditions contraindicating the use of drugs like-active GERD, uncontrolled vomiting, recent history of apnea,and active respiratory issues. 7.Nasal deformities-spur and deviated nasal septum. 8.Uncooperative patients. 9.Surgery for more than two hours. 10.Gut surgery

Design outcomes

Primary

MeasureTime frame
To compare parenteral separation and mask acceptance with ketamine and midazolam when combined with dexmedetomididne repectively, in nebulized form.Timepoint: 4 hours—

Secondary

MeasureTime frame
1.The level of sedation when child is first seen in the operating room. 2.Acceptance of IV cannulation. 3.Analgesia,sedation at emergence and wake up behaviour.Timepoint: 4 hours—

Countries

India

Contacts

Public ContactTanvi Dhiman

Dr. Rajendra Prasad Government Medical College, Kangra at Tanda

versha2u@yahoo.co.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026