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A clinical trail to study the effects of two tablets in patients with tooth ache during root canal treatment.

COMPARATIVE CLINICAL EVALUATION OF EFFECT OF PREOPERATIVE ORAL TRAMADOL AND KETOROLAC ON THE SUCCESS OF INFERIOR ALVEOLAR NERVE BLOCK IN PATIENTS WITH SYMPTOMATIC IRREVERSIBLE PULPITIS -A RANDOMIZED CLINICAL TRIAL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/05/013763
Enrollment
70
Registered
2018-05-08
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- symptomatic irreversible pulpitis

Interventions

Intervention1: tramadol: 50mg one tablet one hour start of Root canal treatment Control Intervention1: ketorolac: 10mg tablet one hour before the start of root canal treatment

Sponsors

Narayana dental college and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.The patients have not taken any analgesics for at least 12 hours before enrollment in the study. 2.Patients with symptomatic irreversible pulpitis of any mandibular posterior teeth. 3.Absence of any periapical radiolucency on radiographs, except for a widened periodontal ligament.

Exclusion criteria

Exclusion criteria: 1.Subjects under 18 years of age. 2.Known allergy, sensitivity, or contraindications to any opioid or non-opioid analgesic NSAIDs and local anesthetics. 3.History of active peptic ulcer within the preceding 12 months. 4.Pregnant or nursing women. 5.History of known or suspected drug abuse. 6.Patients who had taken NSAIDs within 12 hours before administration of the study drugs. 7.Patients with a history of significant medical conditions. 8.Patients unable to give informed consent. 9.Patients having pain in more than 1 mandibular posterior teeth

Design outcomes

Primary

MeasureTime frame
Evaluation of pain during access opening of Root canal treatment after giving inferior alveolar nerve blockTimepoint: 15 minutes 30 minutes 45 minutes After administration of inferior alveolar nerve block

Secondary

MeasureTime frame
pain free root canal treatmentTimepoint: after 1hr

Countries

India

Contacts

Public ContactDr Suneel kumar Chinni

Narayana dental college and hospital

lavanyamds@gmail.com9346567413

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026