Health Condition 1: null- Acute, uncomplicated bacterial tonsillitis
Conditions
Interventions
Intervention1: Levofloxacin: Tab Levofloxacin 500 mg OD for 5 days
Control Intervention1: Cefpodoxime Proxetil: TabCefpodoxime proxetil 200 mg BD for 5 days
Sponsors
Kempegowda Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: • Subjects of either gender between 10 - 55 years diagnosed as acute bacterial tonsillitis as confirmed by throat swab. • Willingness to give written informed consent and availability for regular scheduled follow up.
Exclusion criteria
Exclusion criteria: • Subjects with suspected viral tonsillitis. • Subjects with complications like quinsy, parapharyngeal abscess, AOM, suppurative cervical adenitis. • Subjects with coexisting LRTIs / sinusitis • Patients with severe renal and/or hepatic dysfunction • Pregnant and lactating women • Those who had taken antibiotics within the previous 48 hours or those who had received long acting penicillins within 2 weeks before enrolment into the study. • Subjects with history of any hypersensitivity/or any SAE, to any of the study medications. • Immunocompromised subjects, and in the presence of disorders associated with muscle weakness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the efficacy of Co-amoxiclav,Cefpodoxime proxetil and levofloxacin in acute ,uncomplicated bacterial tonsillitisTimepoint: 18 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the tolerability of study medicationsTimepoint: 18 months | — |
Countries
India
Contacts
Public ContactSuja Xaviar
Kempegowda institute of Medical Sciences
Outcome results
None listed