Efficiency of mifepristone to facilitate vaginal delivery

Efficacy of oral mifepristone in pre-induction cervical ripening and induction of labour. - EM-PCR

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/05/013743

Enrollment

200

Registered

2018-05-07

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Pregnant patients after 40 weeks, to assess the effect of drug on labour

Interventions

Intervention1: mifepristone 200mg, maximum 2 doses: Mifepristone 200mg given orally 24 hours after EDC and repeated after 24 hours if required Control Intervention1: Comparator Agent- no drug given: N

Eligibility

Inclusion criteria

Inclusion criteria: Singleton pregnancy, cephalic presentation Gestational age after 40 weeks No cephalopelvic disproportion Normal latest USG Reactive NST Intact membranes Bishop score Without any medical complications

Exclusion criteria

Exclusion criteria: Myoma/Uterine surgery Parity more than 3 Severe hypertension or preeclampsia Prior cesarean deliveries Diabetes Impaired renal,adrenal or hepatic function Fetal malformation Breech presentation Cephalopelvic disproportion

Design outcomes

Primary

Measure	Time frame
Primary Outcome 1. Improvement in Bishop,s score 2. Time interval between induction and delivery 3. Requirement of induction 4. Requirement of augmentation 5. Cesarean rate 6. Failure of induction Timepoint: till delivery	—

Secondary

Measure	Time frame
Any maternal or fetal side effectsTimepoint: till patient is discharged from the hospital	—

Countries

India

Contacts

Public ContactDR JAYASREE S

Government Medical College,Kozhikode.

drjayasreerajmohan@gmail.com9446007583

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026