Health Condition 1: null- Patients with rehumatic heart disease undergoing valve replacement surgery.
Conditions
Interventions
Intervention1: Injection of dexmedatomidine.: Approximately 10 minutes prior to onset of cardiopulmonary bypass, patients received a bolus dose of the dexmaditomidine, 1 µg/kg in 100 ml normal saline
Sponsors
AIIMS New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: 1 patients suffering from rheumatic mitral valve disease with atrial fibrillation, scheduled for routine mitral valve replacement surgery.
Exclusion criteria
Exclusion criteria: 1 Patients with HR of 2 LA size >60mm 3 NYHA IV 4 Sick sinus rhythm 5 Atrioventricular block 6 Serum creatinine >200mmol/l 7 Elevated liver enzymes 8 Concomitant coronary artery disease 9 Moderate to severe LV dysfunction 10 Redo and emergency surgery 11 Patients on mechanical ventilation/ intra-aortic balloon pump
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart rate and rhythmTimepoint: Base line, just before onset of CPB, after aortic cross clamp release, after completion of surgery, at the time of extubation, at the time of shifting out of ICU. | — |
Secondary
| Measure | Time frame |
|---|---|
| HR and rhythm at the time of shifting to the ward from ICU, duration of mechanical ventilation and ICU stay, and complications in consequence to AF if any.Timepoint: ICU shifting to shifting in post operative ward. | — |
Countries
India
Contacts
Public ContactUmmed Singh
AIIMS New Delhi
Outcome results
None listed