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to determine the appropriate level of positive pressure ventilation during laparoscopic gall bladder surgery

DETERMINATION OF OPTIMAL PEEP TO REVERSE PNEUMOPERITONEUM-INDUCED CHANGES IN RESPIRATORY MECHANICS & ITS EFFECT ON ELIMINATION OF VOLATILE ANAESTHETICS IN PATIENTS UNDERGOING LAPAROSCOPIC CHOLECYSTECTOMY.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/05/013717
Enrollment
90
Registered
2018-05-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- healthy patients undergoing cholecystectomy

Interventions

Intervention1: POSITIVE END EXPIRATORY PRESSURE(PEEP): APPLICATION OF PEEP OF 0, 5, 10 CM H2O IN EACH GROUP RESPECTIVELY AND COMPARING THE CHANGE IN COMPLIANCE DUE TO PEEP AMONG THE GROUPS Control Int

Sponsors

batra hospital research institute
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with ASA status I & II Patients with BMI 25-30 kg/m2 Patients posted for laparoscopic cholecystectomy under G.A.

Exclusion criteria

Exclusion criteria: Patients with History of Asthma/COPD. Patients with comorbid diseases that may increase intra-abdominal pressure. Patients with Morbid obesity. Patients on bronchodilator therapy/ steroid therapy. Patients with preoperative anaemia ( Pregnant or lactating women. Patients with psychological disorders/unfit to give informed consent. Patients with ASA status 3 and 4.

Design outcomes

Primary

MeasureTime frame
CHANGES IN RESPIRATORY COMPLIANCE AND AIRWAY RESISTANCETimepoint: before and after pneumoperitoneum, after application of PEEP

Secondary

MeasureTime frame
To observe the effect of PEEP on elimination time of volatile anaesthetic agent (isoflurane) in this group of patients.Timepoint: At the end of surgery

Countries

India

Contacts

Public Contactdr khushboo

Batra hospital & medical research institute

gurha.pavan@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026