Health Condition 1: null- Acute respiratory failure
Conditions
Interventions
Intervention1: Group S: patients receiving mechanical ventilation by SIMV ( synchronised intermittent mandatory ventilation) mode
Control Intervention1: Group P: patients receiving mechanical ventilat
Sponsors
Sulagna Bhattacharjee
Eligibility
Inclusion criteria
Inclusion criteria: Patients with acute respiratory failure requiring mechanical ventilation for at least three days or more admitted in an intensive care unit (ICU) of a tertiary care teaching hospital (AIIMS, New Delhi) Patients who have been receiving mechanical ventilation for less than 12 hours before recruitment will be included in this study
Exclusion criteria
Exclusion criteria: 1. Patients suffering from neuromuscular diseases 2. Use of neuromuscular blockade to facilitate mechanical ventilation 3. BMI less than 18.5kg/m2 4. Obesity (BMI more than 30kg/m2) 5. Severe ARDS (as per Berlin definition) 6. Previous chest wall surgery 7. Pregnancy 8. History of mechanical ventilation in the past 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the change in diaphragmatic thickness at day 3 between patients on SIMV-PS ventilation & PRVC ventilationTimepoint: To compare the change in diaphragmatic thickness at day 3 between patients on SIMV-PS ventilation & PRVC ventilation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The change in diaphragmatic thickness at day 1, 2,& 7 between patients on SIMV-PS ventilation & PRVC ventilation 2. The change in diaphragmatic thickness at the time of extubation between patients on SIMV-PS ventilation & PRVC ventilation 3. The change in quadriceps muscle thickness at day 1,2,3 &7 between patients on SIMV-PS ventilation & PRVC ventilation 4. The length of ICU stay & ICU mortality between two groups of patients Timepoint: Days 1,2,3 & 7 | — |
Countries
India
Contacts
Public ContactSulagna Bhattacharjee
AIIMS, New Delhi
Outcome results
None listed