Health Condition 1: null- Pregnant patients with hypertension
Conditions
Interventions
Intervention1: hydralazine: 5 mg intravenous over 2 minutes
Control Intervention1: Labetalol: 20 mg intravenous over 2 minutes
Sponsors
Department of Anaesthesiolgy
Eligibility
Inclusion criteria
Inclusion criteria: 1. patients with systolic blood pressure more than or equal to 160 mmHg and/or diastolic blood pressure more than or equal to 110 mmHg 2. single or multiple pregnancy 3. gestational age >24 weeks
Exclusion criteria
Exclusion criteria: 1. patients who did not consent 2. any known allergy to drugs used (hydralazine and labetalol)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| time taken to reach adequate control of blood pressure (systolic blood pressure 140-150 mmHg and/or diastolic blood pressure 90-100 mmHg)Timepoint: every 2 minutes till control of blood pressure achieved | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. efficacy of drugs used (number of doses required for adequate control of blood pressure) 2. number of patients who achieved adequate control of blood pressure 3. incidence of persistent hypertension 4. adverse effects of drugs used 5. maternal outcomes 6. fetal outcomesTimepoint: every 10 minutes till adequate control of blood pressure | — |
Countries
India
Contacts
Public ContactRanju Singh
Lady Hardinge Medical College
Outcome results
None listed