Health Condition 1: null- Patients undergoing trans-sphenoidal resection of pituitary gland tumors
Conditions
Interventions
Intervention1: Lignocaine ( L group ): intravenous bolus of preservative free lignocaine(1% preparation) 1.5mg/kg given just before induction followed by a continuous infusion of 1.5mg/kg/hr
Control I
Sponsors
Post graduate institute of medical education and research
Eligibility
Inclusion criteria
Inclusion criteria: American Society of Anesthesiologist physical status 1/2 patients between age group of 18 to 65 years undergoing trans sphenoidal surgery for pituitary gland tumor at post graduate institute for medical education and research, Chandigarh were included in the study
Exclusion criteria
Exclusion criteria: 1. Patients with adverse reaction to lignocaine, 2. Patients with renal or liver insuffiency, heart block or arrhythmias, 3. Patients on concurrent treatment with class 1 anti-arrhythmic and 4. Patients undergoing revision surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of the effects of lignocaine infusion on the quality of emergence in patients undergoing trans sphenoidal resection of pituitary tumors using an abbreviated emergence score comprising of mean arterial pressure, heart rate, cough and agitationTimepoint: time from switching off of anesthetic agents (T0) to tracheal extubation (T1) | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative hemodynamic stabilityTimepoint: Hemodynamic parameters were recorded at baseline, post induction, post intubation, infiltration of nasal mucosa, insertion of speculum, at sphenoid bone and stellar ridge dissection, switching off of anesthetic agents, at the time of extubation, every 5mins post extubation for 30mins;Sparing effect on volatile anesthetic requirementTimepoint: Minimum alveolar concentration required to maintain bisect real index (BIS) between 40 -60 was noted every 5minutes;Time to emergence from anesthesiaTimepoint: T0 to T1 | — |
Countries
India
Contacts
Public ContactDeepika jain
Department of anesthesia and intensive care
Outcome results
None listed