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â??Effect of Brinzolamide eyedrops used for control of glaucoma in operated corneal transplantation patients

â??Effect Of Topical Brinzolamide On Corneal Endothelium In Post Penetrating Keratoplasty Patients with glaucomaâ??

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/05/013698
Enrollment
50
Registered
2018-05-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients of Post Penetrating keratoplasty with glaucoma

Interventions

Intervention1: Dr. Noopur Gupta: Dr. Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi Control Intervention1: Dr. Noopur Gupta: Dr. Rajendra Prasad Centre for Ophthalmic Sciences,AIIMS,

Sponsors

All India Institute of Medical Sciences New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with pre-existing glaucoma or post PK glaucoma 2. Patients requiring two anti-glaucoma medications ( eye drop timolol and eye drop brinzolamide) for IOP control 3. Age > 18 years 4. Patients giving consent 5. Willing for follow-up

Exclusion criteria

Exclusion criteria: 1. Not giving consent 2. Not willing for follow-up 3. Decompensated graft

Design outcomes

Primary

MeasureTime frame
Corneal graft status and status of endothelium ( specular,ASOCT,and Confocal MicroscopyTimepoint: Baseline, 3 month, 6 month and 1 year—

Secondary

MeasureTime frame
Introcular pressure,graft clarity, visual acuity Timepoint: Baeline, 3 months, 6 months, 1 year—

Countries

India

Contacts

Public ContactDr Noopur Gupta

All India Institute of Medical Sciences

noopurgupta@hotmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026