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changes in left heart relaxation after giving anaesthesia

Changes in left ventricular Diastolic function under anaesthesia: A cross sectional study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/05/013696
Enrollment
112
Registered
2018-05-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- patients posted for surgery

Interventions

Sponsors

MAHATMA GANDHI MEDICAL COLLEGE AND RESEARCH INSTITUTE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age >21 or American Society of Anesthesiologistâ??s physical status classification 1 and 2. Patients without left ventricular systolic dysfunction. Patient undergoing major elective surgery lasting more than two hours.

Exclusion criteria

Exclusion criteria: Poor ECHO window BMI more than30 kg/m2 severe pulmonary disease Patients with expected blood loss greater than allowable blood loss

Design outcomes

Primary

MeasureTime frame
To study the changes in left ventricular diastolic function in patients undergoing elective major surgeries under various types of anaesthesia. To quantify changes in left ventricular diastolic function in terms of the, E (Mitral E velocity), A (Mitral A velocity), E/A ratio, e/ (Septal/lateral e/ Mitral annular velocity), E/e/ ratio, LA Volume index, TR (Tricuspid) velocity as assessed by Transthoracic Echocardiography.Timepoint: TIVA- ONE MINUTE AFTER INDUCTION INHALATION ANAESTHESIA- AFTER STEADY STATE INTRAVENOUS PLUS INHALATIONAL- ONE MINUTE AFTE R IV AND STEADY STATE AFTER INHALATIONAL REGIONAL WITH GA- AFTER ESTABLISHING BOTH SPINAL- 10 MINUTES AFTER SPINAL EPIDURAL- 20 MIN AFTER EPIDURAL AFTER ESTABLISHING PERIPHERAL NERVE BLOCK

Secondary

MeasureTime frame
noneTimepoint: none

Countries

India

Contacts

Public ContactHemanth Kumar V R

Mahatma Gandhi Medical College and Research Institute

rshankarm@gmail.com9789454016

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026