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Comparison of three drugs pethidine,butorphanol,dexmedetomidine for treatment of shivering under spinal anaesthesia

Comparison of intravenous pethidine, butorphanol and dexmedetomidine for treatment of shivering under spinal anaesthesia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/05/013684
Enrollment
150
Registered
2018-05-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA I/II/III

Interventions

Intervention1: Intravenous Pethidine, Butorphanol And Dexmedetomidine For Treatment Of Shivering Under Spinal Anaesthesia: The cases will be randomly divided into 3 groups (50 patients in eac

Sponsors

Bhagat Phool Singh Government Medical College For Women
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age 18-65 years( any gender) 2.American society of Anaesthesiologists (ASA) grade I , II &III physical status 3.Lower limb surgeries, inguinal, abdominal, urological and gynaecological procedures under spinal anaesthesia, who develop shivering during intra-operative and postoperative period (up to 2 hours) will be included in the study.

Exclusion criteria

Exclusion criteria: 1.Patients with hypothyroidism or hyperthyroidism 2.Morbid Obesity (BMI > 40 kg/m2) 3.Fever (axillary temperature > 37 0 Celsius) 4.History of allergy to drugs. 5.Coagulation disorders 6.Patients with significant neurological, psychiatric, neuromuscular, cardiovascular, pulmonary, renal or hepatic diseases.

Design outcomes

Primary

MeasureTime frame
Primary outcome will be to compare the efficacy and response rates of pethidine, butorphanol and dexmedetomidine.Timepoint: The time taken for cessation of shivering will be recorded at 1 minute interval till 5 min and thereafter upto 30 minutes.

Secondary

MeasureTime frame
1.To monitor the vital parameters in all the three groups and compare them subsequently. 2.To record the incidence of recurrence in all the three groups. 3.To record and compare the incidence of adverse effects such as nausea, vomiting, sedation, etc. amongst the three groups. Timepoint: Maximum Upto Two Hours

Countries

India

Contacts

Public ContactGarima Sharma

Bhagat Phool Singh Government Medical College For Women

pranavbansal1@gmail.com8222007555

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026