Health Condition 1: null- Patients with traumatic brain injury coming for surgery Health Condition 2: S065- Traumatic subdural hemorrhage
Conditions
Interventions
Intervention1: NIL: NIL
Sponsors
National Institute of Mental Health And Neurosciences
Eligibility
Inclusion criteria
Inclusion criteria: Patients of either sex, aged between 18- 60 years with mild, moderate and severe traumatic brain injury (TBI) presenting for surgery within 48 hours of trauma .
Exclusion criteria
Exclusion criteria: Patients who are hemodynamically unstable, patients with relative refusing to give consent, patients in whom BIS recording is not possible, patients with anticipated difficult airway, patients history of severe cardiac, pulmonary, liver or renal disease, or obesity (body mass index >30) and pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the dose requirement of propofol for induction of anaesthesia in patients with TBI undergoing surgery using bilateral BIS.Timepoint: At the end of induction , when BIS value decreases to less than or equal to 40 on the uninjured side. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To determine the baseline BIS on the injured and non-injured side in all patients of TBI undergoing surgery 2. To determine the difference in propofol requirement in male and female patients with TBI. 3. To determine the difference between preoperative and postoperative BIS 4.The difference between preoperative and postoperative BIS and its correlation with short term outcome (GOSE). Timepoint: 1.At the beginning of induction. 2. At the end of the anaesthetic induction. 3. At the end of the surgical procedure. 4.At the end of 30 days from recruitment | — |
Countries
India
Contacts
Public ContactDr Seham Syeda
National Institute of Mental Health And Neurosciences
Outcome results
None listed