Health Condition 1: null- Healthy patient fit to undergo surgery Health Condition 2: C269- Malignant neoplasm of ill-definedsites within the digestive system
Conditions
Interventions
Intervention1: Group C: 20 ml Inj Ethanol (50%) with 5 ml 0.25% bupivacaine and 40 mg Triamcinolone will be injected bilaterally around celiac axis.
Control Intervention1: Group D: Pharmacological man
Sponsors
All India Institute of Medical Sciences AIIMS
Eligibility
Inclusion criteria
Inclusion criteria: 40 patients of American Society of Anesthesiologist (ASA) physical status I, II and III of age group >18 years of either sex admitted at Dr BRA IRCH AIIMS and scheduled to undergo curative surgeries for pancreatic, stomach and gall bladder carcinoma but found unresectable at the time of laparotomy under general anaesthesia
Exclusion criteria
Exclusion criteria: 1. Patient refusal 2. Respiratory insufficiency 3. Haemodynamic instability 4. Abnormal thyroid function 5. Renal or hepatic insufficiency, 6. History of any chronic pain 7. Unstable personality and abuse liability.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the analgesic efficacy of intraoperative celiac plexus neurolysis with pharmacological therapy for management of postoperative pain on day 1, 2 and 3 in patients with unresectable pancreatic, stomach and gall bladder cancer.Timepoint: Postoperative day 1,2 and 3 | — |
Secondary
| Measure | Time frame |
|---|---|
| Cumulative morphine consumption Severity of pain and quality of lifeTimepoint: At 1,3 and 6 months of neurolytic procedure. | — |
Countries
India
Contacts
Public ContactVinod Kumar
AIIMS
Outcome results
None listed