Skip to content

Effect of Exercises in improving the overall health and heart functions in Patients following a heart attack

Effect of Aerobic Interval Training (AIT) in improving functional capacity and LV remodelling in post-MI Patients- a Randomized Controlled Trial - REMAIN

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/05/013649
Enrollment
256
Registered
2018-05-03
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients with Myocardial infarction who under went Angioplasty, medically stable.

Interventions

Intervention1: Aerobic Interval Training (AIT) based Cardiac Rehabilitation: Intervention Group will receive Aerobic interval training exercises 2 to 3 times per week for 12 weeks. Control Interventio

Sponsors

Christian Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All Adult Participants who are 65 years of age or below, treated for acute coronary syndrome and medically stable at discharge

Exclusion criteria

Exclusion criteria: Participants with contraindications to treadmill testing Participants who are physically unable to walk- suffering from lower limb and hip injuries, Osteoarthritis of lower limb and spine, myoneuropathies, Unstable angina Uncontrolled HTN (SBP >160 &/or DBP >100mmHg) Uncontrolled dysrhythmias Decompensated heart failure (not evaluated or effectively treated) Severe stenotic or regurgitant valvular disease Hypertrophic cardiomyopathy Poor left ventricular function (EF angina or ischemia at low workloads Acute infection or related symptoms, Not willing to follow up

Design outcomes

Primary

MeasureTime frame
1) Functional capacity as measured by METS and Heart rate recovery at 1 min by Bruce protocol exercise stress test, 6min Walk distance (6MWD) and VO2 max 2) Cardiac functions as measured by ECHO parameters- LV volumes, LV ejection fraction, LV medial global longitudinal strain (GLS), LV e/eâ?? and LV wall motion score index. Timepoint: Baseline and at 12 weeks.

Secondary

MeasureTime frame
1. Improvement in cardio-metabolic profile (blood sugars, lipid profile) 2. Improvement in Waist to Hip Ratio (WHR) and or Body Mass Index (BMI) 3. Decreased resting heart rate and blood pressure Timepoint: 12 weeks

Countries

India

Contacts

Public ContactDr Muralidar Babi

Christian Medical College

tharion@cmcvellore.ac.in9443722621

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026