Health Condition 1: null- Children with Steroid sensitive Nephrotic Syndrome with infrequent relapses
Conditions
Interventions
Intervention1: Reduced dose of steroids for treatment of relapses in idiopathic Steroid sensitive nephrotic children as compared to standard doses: to determine if reducing the total dose of steroids
Sponsors
Suprita Kalra
SK Patnaik
Eligibility
Inclusion criteria
Inclusion criteria: all children with idiopathic nephrotic syndrome on stable immunosuppression(either long term alternate day steroids,levamisole or mycophenolate mofetil) or on no immunosuppresion for last 6 months with infrequent relapses defined as less than 2 relapses in last 6 months
Exclusion criteria
Exclusion criteria: •children started on a steroid sparing agent in last 6 months due to frequent relapses or steroid dependence, •Children with steroid resistant nephrotic syndrome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of frequent relapsers on the reduced dose regime as compared to standard regime Number of relapses in children in whom steroid dose is reduced to 1mg/kg alternate day for 4 weeks instead of the standard 1.5 mg/kg/day alternate day in 6 months Timepoint: 6 months follow up of each child since enrollment | — |
Secondary
| Measure | Time frame |
|---|---|
| Â Cumulative steroid dose in two groups for 6 months Timepoint: 6 months follow up of each child since enrollment | — |
Countries
India
Contacts
Public ContactSuprita Kalra
Armed Forces Medical College
Outcome results
None listed