Useful bacteria and laser in Gum Disease

Efficacy of local application of probiotics with and without photodynamic therapy as an adjunct to scaling and root planing a clinico microbiological study.

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/05/013597

Enrollment

100

Registered

2018-05-02

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- chronic periodontitis

Interventions

Intervention1: probiotics photo dynamic therapy: probiotics-lactobacillus retueri photo dynamic therapy - toludine blue agent Intervention2: Scaling: Ultrasonic scaling and Root planing once Control

Eligibility

Inclusion criteria

Inclusion criteria: 1)Age limit 25 to 60 years. 2)Patient with chronic periodontitis with a probing pocket depth >=5 mm 3)Patients who are systemically healthy are included. 4)Atleast a minimum of 20 Permanent natural teeth should be present.

Exclusion criteria

Exclusion criteria: 1)Patients with ongoing antibiotic therapy. 2)Pregnancy, lactating and smoking. 3)Patients undergone surgical or nonsurgical therapy with in 6months prior the study. 4)Patients who are deemed to be uncooperative.

Design outcomes

Primary

Measure	Time frame
Primary outcome: RAL (Relative attachment level) gain. secondary outcome variable will be PI, GI ,BOP and probing depth To test the hypothesis of adjunctive probiotics and photo dynamic therapy being able to improve non surgical periodontal therapy. Timepoint: baseline , 3 months	—

Secondary

Measure	Time frame
Gingival index, Bleeding index, Plaque indexTimepoint: Baseline, 3 months	—

Countries

India

Contacts

Public ContactDr BV Ramesh Reddy

Narayana dental college and hospital

perioramesh@yahoo.co.in9849798990

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026