To compare the analgesic effect of buprenorphine through epidural and trandermal routes in patients undergoing hysterectomy.

POSTOPERATIVE ANALGESIA WITH EPIDURAL INFUSION OF BUPRENORPHINE VERSUS TRANSDERMAL BUPRENORPHINE IN TOTAL ABDOMINAL HYSTERECTOMY: A COMPARATIVE STUDY - PAEVT

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/05/013594

Enrollment

174

Registered

2018-05-01

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Undergoing Hysterectomy

Interventions

Intervention1: Transdermal buprenorphine patch: Postoperative analgesia with Transdermal buprenorphine patch after hysterectomy Intervention2: Epidural buprenorphine infusion: Epidural buprenorphine i

Eligibility

Inclusion criteria

Inclusion criteria: a) Age between20 and 65 years. American Society of Anaesthesiologists ASA I OR II. Expected hospital stay after intervention atleast for 72 hrs. Weight 45kg -65kg.

Exclusion criteria

Exclusion criteria: Any chronic pain syndromes. Chronic obstructive pulmonary disease. Any history of hypersensitivity to opioids or patch additives. Obstructive sleep apnoea. Psychiatric disorders which impact on appropriate data collection. Surgeries lasting for more than 2 hours.

Design outcomes

Primary

Measure	Time frame
Postoperative analgesia will be assessed using numerical rating scale.Timepoint: 2hr, 4hr, 12hr, 24hr,36hr, 48hr, 60hr, 72hr after surgery	—

Secondary

Measure	Time frame
side effects like nausea, vomiting, pruritus, headache, dizinessTimepoint: 2hr, 4hr, 12hr, 24hr,36hr, 48hr, 60hr, 72hr after surgery	—

Countries

India

Contacts

Public ContactBinu Sajid

Government Medical College Kozhikode

binusajid@yahoo.com919447324632

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026