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To investigate the potential association of plasma Chromogranin and candidate SNPs in the Chromogranin gene with early-onset MI in an Indian population.

Molecular and genetic links of chromogranin A with early myocardial infarction.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/05/013566
Enrollment
1000
Registered
2018-05-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: null- Confirmed MI subjects, â?¤ 40 years old

Interventions

None listed

Sponsors

Dr Ajit Mullasari
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Confirmed MI subjects, <= 40 years old

Exclusion criteria

Exclusion criteria: Cancer or Hepatitis positive or HIV positive

Design outcomes

Primary

MeasureTime frame
To minimize the effects of aging-related confounding factors on the disease association and increase the chance of detecting pathogenetic role for CHGA in MI. Timepoint: To minimize the effects of aging-related confounding factors on the disease association and increase the chance of detecting pathogenetic role for CHGA in MI.—

Secondary

MeasureTime frame
To minimize the effects of aging-related confounding factors on the disease association and increase the chance of detecting pathogenetic role for CHGA in MI. To detect whether plasma CHGA level and certain CHGA SNPs or haplotypes are associated with early-onset MI. Timepoint: To minimize the effects of aging-related confounding factors on the disease association and increase the chance of detecting pathogenetic role for CHGA in MI. To detect whether plasma CHGA level and certain CHGA SNPs or haplotypes are associated with early-onset MI.—

Countries

India

Contacts

Public ContactDr Ajit Mullasari

The Madras Medical Mission

clireco@mmm.org.in04426565974

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026