Health Condition 1: null- ASA Grade I and II Health Condition 2: K802- Calculus of gallbladder without cholecystitis
Conditions
Interventions
Control Intervention1: Ropivacaine plus dexmedetomidine: to compare and evaluate the effects of intraperitoneal instillation of 0.25% levobupivacaine plus dexmedetomidine versus 0.25% ropivacaine plus
Sponsors
Govt Medical College Amritsar
Eligibility
Inclusion criteria
Inclusion criteria: 1. All patients of 18 - 65 years of either sex 2. All ASA grade I and II admitted in the Surgery department. 3. Patients posted for laparoscopic cholecystectomy surgery under general anaesthesia
Exclusion criteria
Exclusion criteria: Pregnant and lactating women Patients with morbid obesity i.e. BMI of 35 Kg/m2. Patients on psychotropic or adrenergic drugs Refusal by patient to enlist in study â?? Patients with chronic pain syndrome. â?? History of previous abdominal surgery. â?? Patients in whom conversion to open cholecystectomy is done for any reason. Allergy to study drug.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| 1. Haemodynamic changes. 2. Any side effects or complications (confusion, dizziness, auditory and visual disturbances, convulsions, hypertension and cardiovascular collapse, tachycardia, arrthymias and respiratory depression). Timepoint: 48 hours | — |
Primary
| Measure | Time frame |
|---|---|
| 1. To study the post-operative analgesic effect of 0.25% levobupivacaine plus dexmedetomidine with 0.25% ropivacaine plus dexmedetomidine with Normal Saline (Control Group) following intra-peritoneal instillation in laparoscopic cholecystectomy. 2. Duration of postoperative analgesia (hours). 3. To assess the need of rescue analgesics in post-operative period in all the groups. Timepoint: 8 hours | — |
Countries
India
Contacts
Public ContactDr Kulwinder Pal Singh
Govt Medical College Amritsar
Outcome results
None listed