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Effect of low dose of oral pregabalin on succinylcholine induced fasciculations and myalgia-A prospective randomized ,double blind,placebo controlled study.

Effect of low dose of oral pregabalin on succinylcholine induced fasciculations and myalgia-A prospective randomized ,double blind,placebo controlled study.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/04/013534
Enrollment
60
Registered
2018-04-27
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H661- Chronic tubotympanic suppurative otitis media Health Condition 2: null- Patients posted for ear and nose surgeries under general anaesthesia.

Interventions

Intervention1: Pregabalin: Pregabalin is a GABA mimetic anticonvulsant drug.It is also used to treat pain caused by nerve damage in people with diabetes (diabetic neuropathy), herpes zoster (post-herp

Sponsors

Hassan Institute of Medical Sciences Hassan
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 and 2 patients Elective patients undergoing ear and nose surgeries under general anaesthesia

Exclusion criteria

Exclusion criteria: History of Hypersensitivity to the study drug. Patients who had received analgesics and sedatives other than those determined by the study protocol. Patients in whom succinylcholine is contraindicated like burns patient,chronic kidney disease patient

Design outcomes

Primary

MeasureTime frame
Fasciculations grading Myalgia gradingTimepoint: Fasciculations grading after one minute of giving succinylcholine Myalgia grading at 24 hours after surgery

Secondary

MeasureTime frame
Time for the first dose of rescue analgesia HR,SBP,DBP,MAP,SPO2,RRTimepoint: Before medication Before induction After induction After intubation at 1st min,5th min and 10th min

Countries

India

Contacts

Public ContactDr Rashmi H D

Dept of Anaesthesiology,Hassan Institute of Medical sciences

rashpravi@gmail.com9482572190

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026