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A study to assess the retinal thickness in normal and glaucoma patients

Comparative analysis of peripapillary retinal nerve fibre layer thickness and macular thickness parameters using spectral domain optical coherence tomography between normal and glaucomatous eyes

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/04/013516
Enrollment
77
Registered
2018-04-27
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Primary Open Angle Glaucoma

Interventions

Control Intervention1: Nil: It is a cross sectional study to determine the diagnostic performance of macular thickness parameters using spectral domain optical coherence tomography to distinguish betw

Sponsors

All India Institute of Medical Sciences Rishikesh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of age >18 years Patients with best corrected visual acuity better than 6/12 and refractive error Patients with open angle on gonioscopy Patient should be willing to give written informed consent

Exclusion criteria

Exclusion criteria: Patients with previous intraocular surgery or laser surgery except uncomplicated cataract surgery within 6 months Patients with coexisting retinal or macular pathology Patients having any pathological condition affecting visual fields eg. Diabetes Mellitus, pituitary lesions Presence of secondary causes of raised Intraocular Pressure eg. Corticosteroid use, trauma, iridocyclitis Patients with neurological diseases, Pathological myopia

Design outcomes

Primary

MeasureTime frame
Average RNFL thickness, RNFL measurements in quadrants, RNFL thickness in 12 clock hour sectors, average macular thickness and average, minimum, and regional GCL/IPL measurements in the glaucomatous and normal subjects.Timepoint: 1 day

Secondary

MeasureTime frame
sensitivity and specificity for each variable in each sector for comparison between normal and glaucoma subjectsTimepoint: 1 day

Countries

India

Contacts

Public ContactDr Kirti Aggarwal

AIIMS Rishikesh

ajaiagrawal@rediffmail.com8607593922

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026