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Comparision between two drugs (fentanyl and dexmedetomidine) in head and neck surgery

Fentanyl versus dexmedetomidine infusion in head and neck free flap surgery for comparison of hemodynamics and anesthetic requirements

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/04/013490
Enrollment
20
Registered
2018-04-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- head and neck free flap surgery

Interventions

Intervention1: fentanyl versus dexmedetomidine: fentanyl 1mcg/kg/hr infusion, dexmedetomidine 1mcg/kg over 10 min as loading dose followed by 0.5mcg/kg/hr infusion as maintenance dose Intervention2: d

Sponsors

Anup Bista
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Male and female patient of 18-60 years of age. 2. patient undergoing head and neck free flap surgery. 3.patient with no serious medical illness.

Exclusion criteria

Exclusion criteria: 1.patient with cardiac disease,renal disease,liver disease 2.patient refusal to take part 3.hypersensitivity to drugs 4.pregnant women 5.history of narcotic abuse

Design outcomes

Primary

MeasureTime frame
TO compare the hemodynamic changes during infusion of fentanyl versus dexmedetomidine in head and neck free flap repair surgery Timepoint: 10 hour—

Secondary

MeasureTime frame
1.Compare the amount of blood loss and need for transfusion during surgery 2.Comapare the amount of additional analgesic required 3.free flap survival up to 7 days 4.adverse effects of drugs 5.surgeons satisfactionTimepoint: 7 days—

Countries

India

Contacts

Public ContactDevalina Goswami

All India Institute of Medical Sciences

drdevalina@gmail.com9971196699

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026