FindTrial
Sign In

Evaluation of effect of Autonomic Nervous System Dysfunction in patients undergoing Knee Replacement Surgery

Evaluation of Haemodynamic Instability in Patients with or without Dysautonomia undergoing Bilateral Total Knee Arthroplasty under Neuraxial Anaesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/04/013477
Enrollment
50
Registered
2018-04-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M170- Bilateral primary osteoarthritis of knee Health Condition 2: null- Patients between the age of 50 to 80 years with bilateral knee osteoarthritis undergoing bilateral total knee arthroplasty

Interventions

None listed

Sponsors

Sir Ganga Ram Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Age : 50 to 80 years 2)Gender : male or female 3)ASA : I-III 4)Patients undergoing total knee arthroplasty under combined spinal epidural anaesthesia

Exclusion criteria

Exclusion criteria: 1)Patient refusal 2)Revision total knee replacement 3)Patients with coagulopathy 4)Local infection

Design outcomes

Primary

MeasureTime frame
The prevalence of dysautonomia in the study groupTimepoint: From perioperative period till 48 hours postoperatively—

Secondary

MeasureTime frame
Correlation between haemodynamic profile changes with dysautonomia in the study group.Timepoint: From perioperative period till 48 hours postoperatively;Correlation of blood transfusion and vasopressor requirement with dysautonomiaTimepoint: From perioperative period till 48 hours postoperatively—

Countries

India

Contacts

Public ContactSouvik Mukherjee

Sir Ganga Ram Hospital

rakeshsaxena3009@gmail.com9810373301

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026