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The Effect of Vitamin C on Post-Operative opioid Requirement in orthopaedic lower limb surgery

The Effect of Ascorbic Acid on Post-Operative opioid Requirement in orthopaedic lower limb surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/04/013474
Enrollment
110
Registered
2018-04-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA I & II

Interventions

Intervention1: Ascorbic Acid: Ascorbic Acid Intervention2: Ascorbic Acid: 1.5gm of ascorbic acid will be given iv to the experimental group. the post operative opioid requirement will be studied betwe

Sponsors

KIMS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Willing patients 2. Age group 18-60years of either sex 3. ASA I & II 4. Lower limb orthopaedic surgery under sub arachnoid block

Exclusion criteria

Exclusion criteria: 1. History of drug abuse 2. Any Suffering from Chronic pain 3. Allergic history to opioids or Ascorbic acid 4. Regular analgesic user or any analgesic taken within 12 hours before surgery. 5. History of renal calculi

Design outcomes

Primary

MeasureTime frame
comparing requirement of opioids during first 24 hours of post-operative period with cotrol groupTimepoint: comparing requirement of opioids during first 24 hours of post-operative period with cotrol group—

Secondary

MeasureTime frame
any complications like allergy reaction to ascorbic acid, phlebitis, pain during infusionTimepoint: 24 hours—

Countries

India

Contacts

Public ContactDr Lingaraj Sahu

KIMS

drlingarajsahu.2008@gmail.com8280166501

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026