Comparison of effect of two local anesthetic solutions in treating diseased teeth with constant sharp pain requiring root canal treatment

Anesthetic efficacy of Articaine and Lidocaine in inferior alveolar nerve block administered with a Computer controlled local anesthetic delivery system in mandibular molars with symptomatic irreversible pulpitis : prospective,double-blinded randomized clinical trial

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/04/013472

Enrollment

100

Registered

2018-04-25

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Bilateral mandibular molars with symptomatic irreversible pulpitis requiring endodontic treatment

Interventions

Intervention1: Inferior alveolar nerve block for bilateral mandibular molars: Inferior alveolar nerve block for bilateral mandibular molars using computer controlled local anesthesia delivery system C

Eligibility

Inclusion criteria

Inclusion criteria: Patients willing to participate in the study Age group : 20 - 45 years Patients having mandibular molars with symptomatic irreversible pulpitis Patients would have not undergone any previous dental local anesthetic experience, in order to be not influenced by a positive or a negative memory. Patient has not taken any medication for the past 2 weeks

Exclusion criteria

Exclusion criteria: Pregnancy Patients who received local anesthesia before the experiment Subjects with systemic diseases Patients on any kind of medication History of psychiatric illness Unco-operative patients Active sites of infection in the area of injection.

Design outcomes

Primary

Measure	Time frame
Anesthetic efficacy of Articaine and LidocaineTimepoint: Any Pain during the endodontic treatment is considered anesthetic failure	—

Secondary

Measure	Time frame
The onset of action and duration of action of Articaine and LidocaineTimepoint: Onset: when the patient starts to feel tingling sensation on the lip Duration : When the patient stops feeling the numbness	—

Countries

India

Contacts

Public ContactDr Dipali Shah

Sinhgad Dental College and hospital Pune

dipali.nagda@yahoo.com9890195100

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026