Checking the amount of a molecule which is responsible for reducing the level of infection by reducing oxidative stress in gum disease patients before and after treatment- a biochemical analysis

Comparative evaluation of the total antioxidant capacity in saliva of patients with chronic generalized periodontitis before and after Scaling and rootplaning and Flap surgery â?? A spectrophotometric analysis

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/04/013471

Enrollment

Registered

2018-04-25

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- chronic generalized periodontitis patients

Interventions

Intervention1: baseline unstimulated saliva and clinical parameters before the treatment: The demographic characteristics of the patients (age and sex), clinical parameters will be recorded initially

Eligibility

Inclusion criteria

Inclusion criteria: Subjects aged 40-50 yrs Subjects with a minimum complement of 20 teeth Subjects will have to possess at least two non-adjacent sites on non-incisor / first molar teeth with probing pocket depths (PPDs) of >= 5 mm, that bleed upon probing (from the pocket base) and which demonstrates radiographic bone loss of >= 30% Subjects who will be indicated for flap surgery

Exclusion criteria

Exclusion criteria: Subjects with any systemic disease Subjects who have undergone any periodontal treatment in the last six months Subjects who have received antibiotics or anti-inflammatory drugs or steroids in the past three months Pregnant or lactating women Subjects who are tobacco or alcohol users Subjects who have taken Vitamin or mineral supplements or Anti-oxidants for the past three months

Design outcomes

Primary

Measure	Time frame
To evaluate the total antioxidant capacity in saliva of patients with chronic generalized periodontitis before and after scaling and root planing and flap surgeryTimepoint: To evaluate the total antioxidant capacity in saliva of patients with chronic generalized periodontitis before and after scaling and root planing and flap surgery	—

Secondary

Measure	Time frame
To evaluate the total antioxidant capacity in saliva of patients with chronic generalized periodontitis afterscaling and root planing and flap surgeryTimepoint: one and half months	—

Countries

India

Contacts

Public ContactAmit Walvekar

Coorg Institute of dental sciences Virajpet

amitakw@rediffmail.com9480085687

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026