None listed
Conditions
Sponsors
Meru S
Eligibility
Inclusion criteria
Inclusion criteria: 1. subjects in the age group of 18 to 30 years. 2. subjects with a DMFT index score of less than 2. 3. subjects with Loe and Silness Gingival index score of 0. 4. subjects willing to volunteer for the study. 5. subjects who are available for the whole study period of 4 months
Exclusion criteria
Exclusion criteria: 1. subjects with history of gastritis and bulimia. 2. subjects with chronic medical illness. 3. subjects with history of allergy. 4. subjects with history of drug intake for last 8 weeks. 5. subjects who smoke or chew tobacco
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pH of Saliva at baseline All subjects in all groups collects the unstimulated saliva in a sterile glass dish for the measurement of baseline pH of the saliva. The subject will give the saliva sample just before being exposed to the test carbonated drink by swishing 100ml of CocaCola in mouth for 2minutes and then drinking it The outcome accessor is blinded to origin of sample (from which group).Timepoint: 0 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| pH of Saliva 5minutes after exposure to test carbonated drink All subjects will be given 100 ml of test carbonated drink, Coco Cola ® to drink. The subject will sip, swish and swallow the drink within 2 minutes. Five minutes after this, each subject will give unstimulated saliva in a sterile dish for measurement of saliva -5minutes after exposure to test carbonated drink. The outcome accessor is blinded to the origin of sample (from which group).Timepoint: 5 minutes;H of Saliva 15minutes after exposure to test carbonated drink All subjects will give unstimulated saliva in a sterile dish for measurement of saliva -15minutes after exposure to test carbonated drink. The outcome accessor is blinded to the origin of sample (from which group).Timepoint: 15 minutes;pH of Saliva 30minutes after exposure to test carbonated drink All subjects from all six (5test and 1comparator) groups will perform the assigned intervention as per schedule at time 15minutes post exposure to carbonated drink and shall give unstimulated saliva in a sterile dish for measurement of saliva -30minutes after exposure to test carbonated drink or in other words 15minutes after assigned intervention. The outcome accessor is blinded to the origin of sample (from which group).Timepoint: 30 minutes;pH of Saliva 45minutes after exposure to test carbonated drink All subjects from all six (5test and 1comparator) groups will perform the assigned intervention as per given schedule at time 15minutes post exposure to carbonated drink and shall give unstimulated saliva in a sterile dish for measurement of saliva -45minutes after exposure to test carbonated drink or in other words 30minutes after assigned intervention. The outcome accessor is blinded to the origin of sample (from which group).Timepoint: 45 minutes;pH of Saliva 60minutes after exposure to test carbonated drink All subjects from all six (5test and 1comparator) groups will perform the assigned intervention as per given schedule at time 15minutes | — |
Countries
India
Contacts
Public ContactMeru S
Uttaranchal Dental and Medical Research Institute
Outcome results
None listed