Treating bone defects in patients with gum diseases using bone graft

Additive effect of plasma rich in growth factors with xenograft in treatment of intra bony defects in patients with chronic periodontitis: A Randomized clinical trial

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/04/013441

Enrollment

Registered

2018-04-24

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Xenograft with Plasma Rich in Growth Factors (PRGF): After administration of local anesthesia, Kirkland flaps will be raised on the facial and lingual surfaces. The defect will be thoro

Eligibility

Inclusion criteria

Inclusion criteria: The individuals aged 30 to 60 years. Systemically healthy condition. Presence of chronic periodontitis (on the basis of the 1999 consensus classification of periodontal diseases). Presence of intra bony defect >=3 mm deep (distance between alveolar bone crest and base of defect on intraoral periapical radiograph). Presence of interproximal probing depth (PD) >=5 mm after phase I periodontal therapy (scaling and root planing [SRP]).

Exclusion criteria

Exclusion criteria: History of periodontal surgical treatment within the last 6 months. Former/current smoker. Pregnant / lactating women Poor oral hygiene and failure to comply with protocol.

Design outcomes

Primary

Measure	Time frame
To compare RAL (Relative attachment level) gain between the groupsTimepoint: Baseline and 6 months	—

Secondary

Measure	Time frame
To compare probing depth,gingival index,radiographic changes between the groupsTimepoint: Baseline and 6 months	—

Countries

India

Contacts

Public ContactSreenivas Nagarakanti

Narayana Dental College and hospital

sreenivasnagarakanti@gmail.com9985664566

Outcome results