Health Condition 1: null- Patients undergoing surgery under general anaesthesia with endotracheal intubation
Conditions
Interventions
Intervention1: Nalbuphine: Injection nalbuphine 0.2mg/kg is given in 5ml bolus 5minutes before induction
Control Intervention1: Fentanyl: Injection fentanyl 2mg/kg is given in 5ml bolus 5minutes befor
Sponsors
Karnataka Institute of Medical Sciences Hubli
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA grade I & II status. 2. Patients giving informed written consent. 3. Patients scheduled to undergo elective laparascopic surgery like appendicectomy, cholecystectomy and hernia repair under general anaesthesia with endotracheal intubation.
Exclusion criteria
Exclusion criteria: 1. ASA III or greater. 2 Pregnant and lactating women. 3. Patients with suspected difficult intubation, allergy to opioids, cardiovascular disease, hepatic or renal disease. 4. Patient with allergy to the study drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean arterial pressureTimepoint: Baseline, 5minutes after drug, after intubation, 1min,2min,3min,4min,5min, 10min and 30min after intubation | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rateTimepoint: Baseline, 5minutes after drug, after intubation, 1min,2min,3min,4min,5min, 10min and 30min after intubation | — |
Countries
India
Contacts
Public ContactMilon Vasant Mitragotri
Karnataka Institute Of Medical Sciences
Outcome results
None listed