Health Condition 1: null- ACUTE CORONARY SYNDROME Health Condition 2: I21- Acute myocardial infarction Health Condition 3: I25- Chronic ischemic heart disease Health Condition 4: I200- Unstable angina
Conditions
Interventions
Intervention1: Morphine: 2 to 8 mg of morphine could be given once every 5 min till side effects happen or symptom subside or maximum of 4 times
Dosage will be reduced to half if age is more than 75 or weight is less than 50 Kg
Control Intervention1: Fentanyl: 1miG/Kg of Fentanyl will be given with a maximum dosage limit of 50 microgram. D
Sponsors
SRI RAMACHANDRA MEDICAL COLLEGE AND RESEARCH INSTITUTION
Eligibility
Inclusion criteria
Inclusion criteria: Patients with acute coronary syndrome and age >18 years
Exclusion criteria
Exclusion criteria: Patients who will be in altered sensorium status due to any other pathology which prohibits them from answering questions Patients who are already on dual anti platelet agents Patients who have been thrombolysed or before reaching ER at SRMC Patients who will not provide consent Patients who would have been administered analgesics in out of hospital settings Patients who receive Gp2b/3a inhibitors in emergency or in ambulance
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Platelet reactivity measured using light transmission aggregometry at SECOND hour between the two groupsTimepoint: SECOND HOUR | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Comparison of pain scale amongst the groups. 2.Comparison of adverse events that include nausea, vomiting, bradycardia, hypotension.Timepoint: second hour | — |
Countries
India
Contacts
Public ContactS NAGENDRA BOOPATHY
SRI RAMAMCHANDRA MEDICAL COLLEGE AND RESEARCH INSTITUTE, CHENNAI
Outcome results
None listed