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we are comparing effect of etomidate,propofol and combination of propofol and ketamine on patients vitals at start of anaesthesia

A comparison of propofol, etomidate and Ketofol means ketamine propofol 1:3 ratio as induction agent A Randomized comparative clinical study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/04/013409
Enrollment
120
Registered
2018-04-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA grade I and II age 18-60yrs both male and female all elective general surgery

Interventions

Intervention1: comparison of propofol etomidate and Ketofol: propofol(2mg/kg)IV etomidate(0.3mg/kg)IV and ketamine(0.5mg/kg)+ propofol(1.5mg/kg)IV 1:3 ratio as induction agent given in 60 seconds stu

Sponsors

Department of anaesthesiology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American society of Anaesthesiologist grade I and II of either sex, weighing 35-70kg elected for general surgeries under general anaesthesia

Exclusion criteria

Exclusion criteria: Patients with history ofadrenal insufficiency, asthma,hypertension,suspected difficult airway, receiving general anaesthesia during the previous week,receiving steroid during the past 6 months,sensitivity to etomidate, propofol or ketamine,sensitivity to egg and soya,pregnancy, Morbidly obese,chronic inflammatory diseases and serious psychiatric,endocrine or neurological illnesses.

Design outcomes

Primary

MeasureTime frame
comparision of haemodynamics in three groupsTimepoint: Haemodynamics were recorded baseline value,after induction,0 min after intubation,1 minute after intubation, 3 min after intubation, 5 min after intubation and 10 min after intubation

Secondary

MeasureTime frame
comparison of side effects and any adverse effectsTimepoint: any adverse effects of drug like pain on injection and myoclonus movement was seen during induction

Countries

India

Contacts

Public ContactMeenakshi machhar

RNT MEDICAL COLLEGE AND ATTACHED HOSPITAL,DEPARTMENT OF ANAESTHESIOLOGY

khemraj10@gmail.com9414759782

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 12, 2026