Homeopathic treatment of knee osteoarthritis

An open randomized controlled clinical trial evaluating the role of additive mother tinctures to individualized homoeopathic treatment of knee osteoarthritis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/04/013395

Enrollment

128

Registered

2018-04-20

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Knee osteoarthritis Health Condition 2: M179- Osteoarthritis of knee, unspecified

Interventions

Intervention1: Indicated homeopathic medicines in centesimal or fifty millesimal potencies plus one of the four following mother tinctures as indicated: Angustura vera, Guaiacum, Stellaria media, and

dosage and repetition depending upon the individual requirement of the cases. In 50 millesimal scale, a single medicated cane sugar globules of poppy seed size (no. 10) shall be dissolved in 90 ml dis

16 doses to be marked on the vial

each dose of 5 ml to be taken after 10 uniformly forceful downward strokes to the vial in 45 ml normal water in a clean cup, to stir well, to take 5 ml of this liquid orally, and to discard rest of th

dosage and repetition depending upon the individual requirement of the c

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age 40-70 years 2. Both sexes 3. Diagnosed knee osteoarthritis as per American College of Rheumatology (ACR) clinical or radiographic classification criteria (sensitivity 91%; specificity 86%): a) Knee pain b) At least 1 of 3: age more than 50 yrs, stiffness less than 30 min, and crepitus on knee motion c) Osteophytes on x-ray knee (AP/lateral view) 4. Patients already undergoing regular oral or topical analgesics or NSAID therapy for painful episodes of osteoarthritis, provided the medications are stopped completely at least 2 weeks prior study entry 5. Providing written informed consent 6. Literate patients; ability to read English and/or Bengali

Exclusion criteria

Exclusion criteria: 1. Severe degeneration of knee joint with marked joint narrowing, varus, or valgus deformity of knee ( >12Â°), evidenced by imaging or other evidences and requiring surgical intervention 2. Non-ambulant patients 3. Self-reported joint disorders other than osteoarthritis (e.g., inflammatory joint disease, specific arthropathy, severe axis deviations or instabilities, joint or skin infections, joint prostheses of the lower limbs) 4. Intra-articular injections within 2 wk before study entry 5. Transplanted knees 6. Recent significant knee surgery within last 6 months 7. Patients who are too sick for consultation 8. Unwilling to take part and not giving consent to join the study 9. Unable to read patient information sheet 10. Diagnosed cases of unstable mental or psychiatric illness or other uncontrolled or life-threatening illness affecting quality of life 11. Pregnancy and lactation 12. Substance abuse and/or dependence 13. Self-reported immune-compromised state, and 14. Undergoing homeopathic treatment for any chronic disease within last 6 months

Design outcomes

Primary

Measure	Time frame
Bengali version of the Knee injury and Osteoarthritis Outcome Score (KOOS) questionnaireTimepoint: At baseline, after 3 months, and after 6 months	—

Secondary

Measure	Time frame
Five individual KOOS subscale scores â?? pain, other symptoms, activity of daily living (ADL), sport or recreation, and knee-related quality of life (QOL)Timepoint: At baseline, after 3 months, and after 6 months;Frequency of add-on Paracetamol and/or NSAIDs (oral/topical) useTimepoint: 6 months	—

Countries

India

Contacts

Public ContactAnaitullah Ahmad Mir

National Institute of Homoeopathy, Ministry of AYUSH, Govt. of India

civildefence12@gmail.com9419039499

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026