Health Condition 1: C768- Malignant neoplasm of other specified ill-defined sites Health Condition 2: null- Patient suffering from cancer and having cancer pain
Conditions
Interventions
Intervention1: Morphine infusion group: Patient will receive intravenous bolus of Morphine 0.05mg/kg body weight followed by intravenous infusion at the rate of 0.025mg/kg/hour. Pain will be reassesse
Sponsors
All India Institute of Medical Sciences AIIMS
Eligibility
Inclusion criteria
Inclusion criteria: Patients of either sex, aged 18-75 years, having severe cancer pain (NRS 7 or more) and are morphine naïve will be included in the study
Exclusion criteria
Exclusion criteria: 1. Patient already receiving morphine or any other opiates. 2.Patients who are having morphine non-responsive/partially responsive pain 3. Patients having brain tumour/ metastasis to brain, liver or renal dysfunction 4. Patient having the bowel obstruction 5. Patients who refuse consent 6. Patient having pure neuropathic pain 7. Patient requiring steroid for managing pain
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the analgesic efficacy of two technique of morphine titration (bolus vs. infusion) for analgesic titration in patients with severe cancer painTimepoint: One week of starting morphine | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the patient satisfaction of the two technique of morphine titration (bolus vs. infusion) for analgesic titration in patients with severe cancer pain.Timepoint: Which technique patient will prefer. | — |
Countries
India
Contacts
Public ContactDr Vinod Kumar
AIIMS
Outcome results
None listed