Health Condition 1: null- Knee osteoarthritis
Conditions
Interventions
Intervention1: Indicated homoeopathic
remedies in centesimal
potencies plus standard physiotherapy: Indicated homoeopathic
medicines in centesimal
potencies and in individualized dosage, as decided ap
dosage and repetition depending upon the individual requirement of the cases. Standard physiotherapy measures will be advised alongside. Duration of therapy: 6 months
Control Intervention1: Placebo, i
Sponsors
National Institute of Homoeopathy Ministry of AYUSH Govt of India
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 50-70 years 2. Both sexes 3. Diagnosed knee osteoarthritis as per American College of Rheumatology (ACR) clinical/radiographic classification criteria, (sensitivity 91%; specificity 86%): a) Knee pain b) At least 1 of 3: age more than 50 yrs, stiffness less than 30 min, and crepitus on knee motion c) Osteophytes on knee x-ray 4. Patients already undergoing regular oral or topical analgesics or NSAID therapy for painful episodes of osteoarthritis, provided the medications are stopped completely at least 2 weeks prior study entry 5. Can read Bengali 6. Providing written informed consent
Exclusion criteria
Exclusion criteria: 1. Severe degeneration of knee joint with marked joint narrowing, varus, or valgus deformity of knee ( >12°), evidenced by imaging or other evidences and requiring surgical intervention 2. Non-ambulant patients 3. Self-reported joint disorders other than osteoarthritis (e.g., inflammatory joint disease, specific arthropathy, severe axis deviations or instabilities, joint or skin infections, joint prostheses of the lower limbs) 4. Intra-articular injections within 2 weeks before study entry 5. Transplanted knees 6. Recent significant knee surgery within last 6 months 7. Patients who are too sick for consultation 8. Unwilling to take part and not giving consent to join the study 9. Unable to read patient information sheet 10. Diagnosed cases of unstable mental or psychiatric illness or other uncontrolled or life-threatening illness affecting quality of life 11. Pregnancy and lactation 12. Substance abuse and/or dependence 13. Self-reported immune-compromised state, and 14. Undergoing homeopathic treatment for any chronic disease within last 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bengali version of the Knee injury and Osteoarthritis Outcome Score (KOOS) questionnaireTimepoint: Baseline, after 3 months and after 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Five individual KOOS subscale scores â?? Pain, other symptoms, ADL, Sport/Recreation, and QOLTimepoint: Baseline, after 3 months and after 6 months;Frequency of add-on Paracetamol and/or NSAIDsTimepoint: Baseline, after 3 months and after 6 months | — |
Countries
India
Contacts
Public ContactSyed Afsar Ali
National Institute of Homoeopathy, Ministry of AYUSH, Govt. of India
Outcome results
None listed