Comparison of two doses of pregabalin for postoperative pain in patients undergoing surgery for breast cancer

Comparison of two doses of pregabalin for postoperative analgesia in patients undergoing surgery for breast cancer

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/04/013295

Enrollment

Registered

2018-04-16

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- UNDERGOING SURGERY FOR BREAST CANCER

Interventions

Intervention1: Pregabalin 75mg group : In this group patients would be given Pregabalin 150 mg 1 hour before the surgery and Pregabalin 75 mg twice a day for 14 days postoperatively.Patients would be

Eligibility

Inclusion criteria

Inclusion criteria: UNDERGOING SURGERY FOR BREAST CANCER ASA I OR II

Exclusion criteria

Exclusion criteria: 1 Allergy to pregabalin 2 Already on gabapentin/pregabalin 3 Any other chronic pain 4 Renal insufficiency 5 Pregnancy 6 Patients who will be receiving any nerve blocks before surgery

Design outcomes

Primary

Measure	Time frame
To evaluate the efficacy of two doses of pregabalin for postoperative pain relief by - NRS score - postoperative analgesic dose requirement Timepoint: At 4 hours, 12 hours, 24 hours and 48 hours postopertively	—

Secondary

Measure	Time frame
To evaluate the efficacy of two doses of pregabalin in chronic neuropathic pain by - NRS mean - Activity - sleep disturbance. Timepoint: At 15 days, 1month and 3 months postoperatively	—

Countries

India

Contacts

Public ContactDr Madhu Dayal

Vardhman Mahavir Medical College and Safdarjung Hospital

drmadhudayal@gmail.com9811271996

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026