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Comparing the postsurgical pain relieving effects of three groups of drugs in patient of open inguinal hernia repair posted under regional anaesthesia.

Comparative study of preoperative oral pregabalin alone,pregabalin with dexamethasone and pregabalin with Vitamin B complex for postoperative analgesic requirement in open inguinal hernia repair under subarachanoid block.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/04/013293
Enrollment
126
Registered
2018-04-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA GRADE 1 ,ASA GRADE 2

Interventions

Intervention1: TABLET PREGABALIN,PREGABALIN WITH DEXAMETHASONE,PREGABALIN WITH VITAMIN B COMPLEX: In Group I, Oral Capsule Pregabalin 300 mg Capsuleand IV placebo in 100ml NS( over 15 minutes) will be

Sponsors

Bhagat Phoot Singh Government Medical College For Women KhanpurKalan SonipatHaryana
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient consented for the study Patient of Age Group : 20-60 years Patients with American society of anaesthesiologists I or II Patient of any gender posted for inguinal hernia repair.

Exclusion criteria

Exclusion criteria: Patients with refusal to enter the study Patients with American society of anaesthesiologists III, IV or V Pregnant females Patient with History of Renal disease Patient with History of seizure or other neurological disorders Patient currently taking Gabapentin or Pregabalin for other medical purpose Patient with known history of allergic reaction to pregabalin from previous use Patients with known history of allergic reaction to vitamin b complex Patients with comorbid diseases like diabetes, hypertension, neurological, psychiatric or neurovascular disorder Patients having absolute contraindication for spinal anaesthesia like raised intracranial pressure, severe hypovolemia, bleeding diathesis and local infection .

Design outcomes

Primary

MeasureTime frame
Primary outcome will be to compare efficacy of drug combinations in prevention of postoperative pain . Timepoint: upto 24 hours

Secondary

MeasureTime frame
Secodary outcome is to compare haemodynamic staus and incidence of side effects.Timepoint: upto 24 hours

Countries

India

Contacts

Public ContactDeepak Gupta

Bhagat Phool Singh Government Medical College For Women Khanpur Kalan,Sonipat,Haryana

meenu297@yahoo.com9467823780

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026