To compare effects of spinal anesthesia when local anesthetic drug given at once to when given twice in devided part of full dose.

Comparision of fractionated dose versus bolus dose of hyperbaric Bupivacaine injection in spinal anaesthesia for elderly patients undergoing lower limb surgeries.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/04/013261

Enrollment

Registered

2018-04-13

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M849- Disorder of continuity of bone, unspecified Health Condition 2: null- Elderly patients undergoing lower limb surgeries.

Interventions

Intervention1: Bupivacaine with dextrose in dose of 0.09mg per centimeter of height once in stat dose.: 0.09mg/cm height bolus Control Intervention1: 0.5% hyperbaric bupivacaine fractionated dose: Fra

Eligibility

Inclusion criteria

Inclusion criteria: Pt with ASA grade 1 and 2.

Exclusion criteria

Exclusion criteria: Pt with coagulation disorders. Pt with any contraindications to SAB. Pt with ASA grade 3 and 4.

Design outcomes

Primary

Measure	Time frame
Duration of pain perception Motor movement loss Heart rate variation Non invasive blood pressure variation Mean arterial pressure variation Timepoint: Duration of pain perception Onset of motor movement loss Intra operative Heart rate variation Intra operative non invasive blood pressure variation Intra operative mean arterial pressure variation	—

Secondary

Measure	Time frame
Comparision of overall hemodynamic stability of elderly pt with fractioned dose of local anaesthetic in spinal anaesthesia to bolus dose.Timepoint: Intraoperative period for vital parameters. Post operative analgesia.	—

Countries

India

Contacts

Public ContactShailesh Mishra

Peoples college of medical sciences and research center, Bhopal

drmahimabatra@gmail.com9131186123

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026