Skip to content

Hypofractionated Radiotherapy in Locally Advanced Carcinomas of the Cervix

Local Control and Toxicity Profile in Patients of Locally Advanced Carcinomas of the Cervix (Stage IIIb Disease) Treated with Hypofractionated Radiotherapy

Status
Active, not recruiting
Phases
Phase 1Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/04/013243
Enrollment
96
Registered
2018-04-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients of hitologically proven cervical cancer

Interventions

Intervention1: Hypofractionated External Beam Radiotherapy: External beam radiotherapy at 2.25 gray per fraction with a total dose of 45Gy in 20 fractions with additional 4.5Gy in 2 fractions with mid

Sponsors

Jawaharlal Institute of Postgraduate Medical Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Histologically confirmed cervical cancer. KPS > 50 Creatinine clearance

Exclusion criteria

Exclusion criteria: History of chemotherapy or radiation to abdomen or pelvis Tumour involving lower third of Vagina History of other cancers. Expected survival less than 3 months Pregnant women Patients with distant metastases

Design outcomes

Primary

MeasureTime frame
Local Tumour ControlTimepoint: 4 weeks after completion of radiotherapy

Secondary

MeasureTime frame
Acute radiation induced toxicitiesTimepoint: Weekly during radiotherapy;Late radiation induced toxicitiesTimepoint: 2 months, 4 months and 6 months after completion of treatment followed by three monthly visits;Local Control & Disease StatusTimepoint: 2 months, 4 months and 6 months after completion of treatment followed by three monthly visits;Overall treatment timeTimepoint: At completion of treatment

Countries

India

Contacts

Public ContactNinad Harish Patil

Jawaharlal Institute of Postgraduate Medical Education and Research

dr_patchu2003@yahoo.co.in9443601748

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026