Comparing three frequencies for phacoemulsification for cataract

Comparison of effective phacoemulsification time and corneal endothelial cell loss using three different ultrasound frequencies in phacoemulsification

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/04/013238

Enrollment

165

Registered

2018-04-13

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- cataract

Interventions

Intervention1: 53 KHz frequency ultrasound: phacoemulsification using 53KHz Control Intervention1: 28 KHz frequency ultrasound: phacoemulsification using 28 KHz Control Intervention2: 42 KHz frequency

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients of age >40 yrs having Grade 4.0-6.9 (LOCS III grading) of senile cataract 2. Patients willing to participate in the study with written consent

Exclusion criteria

Exclusion criteria: 1. Patients with pre-operative endothelial cell density count less than 1500 cells/mm2 . 2. Eyes with any kind of corneal dystrophy or corneal scars preventing visualisation of cataract for reliable grading 3. Raised intraocular pressure ( > 21 mmHg) 4. Previous intraocular surgery

Design outcomes

Primary

Measure	Time frame
EFFECTIVE PHACOEMULSIFICATION TIME Timepoint: Peroperative	—

Secondary

Measure	Time frame
TOTAL ULTRASOUND TIME Timepoint: PER OPERATIVE;Best Corrected Visual AcuityTimepoint: Preoperatively,1 week, 1 month;Central Corneal Thickness(CCT)Timepoint: Preoperatively,1 week, 1 month,3 months, 6 months ,9 months, 1 year;Coefficient of variation of cell size(CV)Timepoint: Preoperatively,1 week, 1 month,3 months, 6 months ,9 months, 1 year;Endothelial Cell Density(CD)Timepoint: Preoperatively,1 week, 1 month,3 months, 6 months ,9 months, 1 year;Hexagonal Cell Count(6A)Timepoint: Preoperatively,1 week, 1 month,3 months, 6 months ,9 months, 1 year;Intraocular PressureTimepoint: Preoperatively,1 week, 1 month	—

Measure

Time frame

TOTAL ULTRASOUND TIME Timepoint: PER OPERATIVE;Best Corrected Visual AcuityTimepoint: Preoperatively,1 week, 1 month;Central Corneal Thickness(CCT)Timepoint: Preoperatively,1 week, 1 month,3 months, 6 months ,9 months, 1 year;Coefficient of variation of cell size(CV)Timepoint: Preoperatively,1 week, 1 month,3 months, 6 months ,9 months, 1 year;Endothelial Cell Density(CD)Timepoint: Preoperatively,1 week, 1 month,3 months, 6 months ,9 months, 1 year;Hexagonal Cell Count(6A)Timepoint: Preoperatively,1 week, 1 month,3 months, 6 months ,9 months, 1 year;Intraocular PressureTimepoint: Preoperatively,1 week, 1 month

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Countries

India

Contacts

Public ContactDr Nisha Bharti

PGIMER & RMLHospital

tarudewan@hotmail.com9810673180

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026