Health Condition 1: null- Uterine Fibroid Female otherwise healthy
Conditions
Interventions
None listed
Sponsors
Asheesh Sachdeva
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion Criteria for cases 1.Female subjects with 18 to 50 years of age (both inclusive) who are in perimenopausal status. 2.Documented evidence of atleast one uterine fibroid lesion of 2 cm3 or greater on ultrasonography. 3.Ability to provide consent. Inclusion Criteria for control 1.Female subjects with 18 to 50 years of age (both inclusive) who are in pre-menopausal status. 2.Documented evidence of no uterine fibroid lesion on ultrasonography. 3.Ability to provide consent.
Exclusion criteria
Exclusion criteria: 1.Pregnant and lactating women 2.Women with a history of abortion or miscarriage in last 6 months 3.Women with history of prior surgery for fibroids (myomectomy) or hysterectomy 4.Women with concomitant use of vitamin D supplements or history of vitamin D supplement within last 3 months 5.Women with concomitant use of hormonal treatment (including oral contraceptives) or history of hormonal treatment within last 3 months 6.Women with concomitant use of drug known to increase the serum prolactin levels [e.g., haloperidol, chlorpromazine, thioridazine, thiothixene (typical antipsychotics); risperidone, amisulpride, molindone, zotepine (atypical antipsychotics); sertraline, fluoxetine, paroxetine, pargyline, clorgyline (antidepressants); buspirone, alprazolam (psychotropics); metoclopramide and domperidone (prokinetics), alpha-methyldopa, reserpine and verapamil (antihypertensive), morphine (opiates)] 7.Women with diabetes mellitus, pituitary and hypothyroidism, chronic renal failure, or psychiatric disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.To determine association of serum Prolactin with uterine fibroid. 2.To determine association of serum Vitamin D3 with uterine fibroid. Timepoint: After completion of subject enrollment | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To determine association of serum Prolactin with number, size & location of uterine fibroids. 2.To determine association of serum Vitamin D3 with number, size & location of uterine fibroids Timepoint: After completion of subject enrollment | — |
Countries
India
Contacts
Public ContactASHEESH SACHDEVA
Artemis Hospital
Outcome results
None listed