Health Condition 1: null- Locally Advanced Cervical Cancer.
Conditions
Interventions
Intervention1: True accelerated radiation alone with reduced overall treatment duration
to Conventional Concomitant Chemoradiation in Locally Advanced Carcinoma Cervix: The s
Sponsors
Dr Debashis Das
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 35 -60yrs 2. No history of Pelvicoperation 3. Pathologically proved carcinoma cervix (FIGO stage 2B to 4A)4.Patient signed consent forms.5. No prior history of malignancy. 6.Karnofsky Performance Status (KPS) >= 70. 7. No prior history of exposure tocytotoxic chemotherapy or radiation. 8. No clinical or radiological evidenceof metastasis at presentation. 9. Adequate bone marrow function: Hb > 10g/dl; WBC > 4000/mm3 (ANC >= 2000/mm3); Platelets >= 1,00,000/mm3.
Exclusion criteria
Exclusion criteria: 1. Age >=60 2. Pregnancy 3. History of Pelvicoperation 4. Stage 4B disease . 5. Karnofsky Performance Status (KPS) <70. 6. Participation in any other study on cancer cervix. 7. Prior pelvic radiation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess and compare the response and safety of true accelerated radiation alone with reduced overall treatment duration to conventional concomitant chemoradiation in locally advanced carcinoma cervix .Timepoint: One Year and Six Months | — |
Secondary
| Measure | Time frame |
|---|---|
| a. Assessment of response b. Detection of recurrence, if any c. Assessment of quality of life d. Assessment of toxicity(acute & late).Timepoint: One Year and Six Months | — |
Countries
India
Contacts
Public ContactDr Debashis Das
Calcutta Medical College, Kolkata
Outcome results
None listed