Health Condition 1: null- patients undergoing lower limb surgeries
Conditions
Interventions
Intervention1: Intrathecal nalbuphine hydrochloride (800 µg)
versus butorphanol (25µg) as adjuvant to hyperbaric bupivacaine: To compare the effect of intrathecal nalbuphine hydrochloride (800 µg)
Sponsors
Sri Guru Ram Das Medical institute of sciences and research
Eligibility
Inclusion criteria
Inclusion criteria: -ASA grade 1 and 2 - patients undergoing lower limb surgeries
Exclusion criteria
Exclusion criteria: - ASA grade III and IV - Patientâ??s refusal to participate in the study - Contraindications to regional anesthesia such as local infections/sepsis at the site of lumbar puncture, space occupying lesions of the brain, anatomical disorders of spine, shock, etc - Hypersensitivity to study drugs - Neurological disorders - Coagulation disorders - Pregnant women - History of opioid dependence
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| duration of postoperative analgesiaTimepoint: duration of postoperative analgesia | — |
Secondary
| Measure | Time frame |
|---|---|
| a.Onset, duration of sensory & motor blockade and to evaluate the hemodynamic changes b. Complications related to procedures, side effects associated with study drugs and sedation scoreTimepoint: a. to evaluate onset, duration of sensory and motor blockade till 24 hours after the surgery b.intraoperative and postoperative hemodynamic stability upto 24 hours after surgery c. complications related to procedure, side effects and sedation score upto 24 hours after surgery. | — |
Countries
India
Contacts
Public ContactDr Keerat Kaur Kullar
professor and head of department
Outcome results
None listed