Health Condition 1: null- Advanced Incurable Breast Cancer in Female
Conditions
Interventions
Intervention1: Radiation: Hypo-Fractionated Radiotherapy Schedule of 26 GY in 5 Fractions with Simultaneous Integrated Boost (6 GY) in Advanced Incurable Breast Cancer: A Prospective Phase I/II Study-
Sponsors
Tata Medical Center
Eligibility
Inclusion criteria
Inclusion criteria: Age �18 years 1. Female 2. Invasive carcinoma of the breast 3. ECOG performance status 0-2 4. Locally advanced breast cancer which is not amenable to curative surgery as decided by multidisciplinary tumour board. 5. Metastatic breast cancer patients: 6. Who are awaiting palliative locoregional radiotherapy for symptom (pain bleeding, ulceration, impending fungation) control. 7. Who have completed a scheduled course of palliative chemotherapy and is felt to benefit from local radiation therapy 8. Able to give informed consent
Exclusion criteria
Exclusion criteria: 1. Breast reconstruction using implants 2. Concurrent cyto-toxic chemotherapy 3. Prior radiation to the chest wall / breast
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ToxicityTimepoint: At one week and four weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of lifeTimepoint: One year;ResponseTimepoint: 3 months | — |
Countries
India
Contacts
Public ContactSantam Chakraborty
Tata Medical Center
Outcome results
None listed