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A clinical trail to study ondansetron on reducing drop in blood pressure after spinal anaesthesia.

Effect of intravenous ondansetron on spinal anaesthesia induced hypotension and bradycardia-A randomised controlled double blinded study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/04/013190
Enrollment
140
Registered
2018-04-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: null- patients without any comorbid diseases

Interventions

Intervention1: Ondansetron: Dose: 4mg Intravenous route once before sub arachanoid block Its an anti emetic drug most commonly used. it is having inhibitory effect on serotogenioc pathways so it might

Sponsors

Dr Geetha CR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiologists (ASA) grade I-II

Exclusion criteria

Exclusion criteria: 1 Patients in whom spinal anaesthesia is contraindicated. 2 Patients having known allergy to ondansetron. 3 Patients having hypertension and coronary artery disease. 4 Patients who are taking selective serotonin reuptake inhibitors (SSRI). 5 Parturients 6 Patients having Autonomic Neuropathy. 7 BMI > 30 kg/m2.

Design outcomes

Primary

MeasureTime frame
To assess the effect of intravenous ondansetron on spinal anaesthesia induced hypotension and bradycardia.Timepoint: 0min, 3mins ,6mins, 9mins, 12 mins, 15mins, 18mins, 21mins, 24mins, 27mins, 30mins.—

Secondary

MeasureTime frame
1) Peri-operative nausea, vomiting. 2) Shivering. Timepoint: 30 mins, 60 mins—

Countries

India

Contacts

Public ContactDr Tatikonda Chandra Mouli

MS Ramaiah Medical College

jageedha@yahoo.com9900482828

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026