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Comparison the effect of two routinely used anesthesia induction agents on contractile function of heart with perioperative echocardiography in patient undergoing elective coronary artery bypass surgery

Comparison the effect of etomidate and thiopentone on left ventricular strain and strain rate at the time of anesthesia induction in patient undergoing elective coronary artery bypass surgery:A randomized double blind controlled study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/04/013172
Enrollment
60
Registered
2018-04-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients with coronary artery disease who underwent coronary artery bypass surgery.

Interventions

Intervention1: Transthoracic echocardiography: Comprehensive transthoracic echocardiography before anaesthesia induction and one minute after injection of study drug along with hemodynamic parameter r

Sponsors

AIIMS New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients between 45 and 70 years of age with normal LV function and acceptable TTE window posted for elective CABG surgery.

Exclusion criteria

Exclusion criteria: Patients with persistent arrhythmia, associated structural heart disease, ejection fraction <50%, congestive cardiac failure, on mechanical ventilation, IABP , redo surgery/ emergency surgery, morbid obesity, difficult airway having problem in mask ventilation, emphysematous chest or any chest deformity with poor window for TTE, signs of actual angina or acute myocardial infarction within the last 30 days, known adrenal insufficiency, history of steroid use in the preceding six months, and those with severe systemic non-cardiac disease other than diabetes and hypertension.

Design outcomes

Primary

MeasureTime frame
strain and strain rate of left ventricle.Timepoint: Just before anaesthesia induction and one minute after injection of study drug.

Secondary

MeasureTime frame
Hemodynamic parameers.Timepoint: Just before anaesthesia induction and one minute after injection of study drug.

Countries

India

Contacts

Public ContactUmmed Singh

AIIMS New Delhi

minati.2002@gmail.com9868398104

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026