Health Condition 1: null- diagnosed cases of intractable epilepsy scheduled for epilepsy surgery belonging to age 7-65 years and ASA 1/2 with good neuropsychological assessment (IQ more than 70), without known allergies
Conditions
Interventions
Intervention1: Desflurane group: In Desflurane group, depth of anaesthesia will be maintained with MAC values of 0.8-1.0 with N2O and opioids. During EcoG recording, N2O will be shut 10 minutes prior
Sponsors
Seth GS Medical College and KEM Hospital
Eligibility
Inclusion criteria
Inclusion criteria: - Diagnosed case of medically intractable epilepsy - Well-defined lesions on MRI (hippocampal sclerosis, either focal cortical dysplasia, tumor or gliosis) with defined concordance on inter ictal electroencephalography (EEG), Video EEG. - Single Neurosurgeon discretion of ECoG guided Epilepsy Surgery - ASA 1/2 - Good Neuropsychological assessment (Intelligent Quotient (IQ) score > 70)
Exclusion criteria
Exclusion criteria: - Patients with doubtful concordance or with a more diffuse surgical substrate - Patients with morbid obesity, pregnancy - ASA 3 and above - Known allergy to the anesthetic drugs used.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the effect of Desflurane and propofol on Electrocorticographic spikes in patients undergoing epilepsy surgeryTimepoint: ECoG spike onset time Total duration of ECoG recording | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the incidence of awareness during surgeryTimepoint: 24 hours postoperatively | — |
Countries
India
Contacts
Public ContactPallavi Gaur
Seth G S Medical College and KEM Hospital
Outcome results
None listed