Health Condition 1: null- Otherwise healthy patients undergoing spine surgery under general anaesthesia
Conditions
Interventions
Intervention1: Sevoflurane: A relatively newer inhalational agent used to administer general anaesthesia for surgeries, including neurosurgeries
Control Intervention1: Isoflurane: An inhalational agen
Sponsors
Vivek Rayadurg
Eligibility
Inclusion criteria
Inclusion criteria: • ASA Class I and II • Elective spine surgery
Exclusion criteria
Exclusion criteria: • Unwilling or not giving consent for study • Difficulties in communication • Extubation more than 2 hours after end of surgery • Patients diagnosed pre-operatively with chronic pain syndromes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the differences in post-operative pain severity, duration and analgesic requirements with Isoflurane- and Sevoflurane- based anesthetic regimens in patients undergoing elective spine surgeryTimepoint: 0, 2, 4, 6, 8, 24, 48 and 72 hours after extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| - To evaluate if there is any difference in pain severity between genders - To evaluate differences in severity of pain with different surgical procedures - To correlate duration of exposure to anaesthetic agent and severity of postoperative pain - To note the time to first independent mobility from bed - To note the time to first feeding - To note the time to feeling completely pain-free - To assess the severity of pain at the time of discharge from hospitalTimepoint: 0, 2, 4, 6, 8, 24, 48 and 72 hours after extubation | — |
Countries
India
Contacts
Public ContactVivek Rayadurg
National Institute of Mental Health and Neurosciences (NIMHANS)
Outcome results
None listed