Health Condition 1: null- Acne Vulgaris Health Condition 2: L088- Other specified local infections of the skin and subcutaneous tissue
Conditions
Interventions
None listed
Sponsors
Investigator Initiated Study
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients with acne of mild to moderate as per the Combined Acne Severity Classification.8 a. Mild acne: fewer than 20 comedones, or fewer than 15 inflammatory lesions or a total lesion count lower than 30 b. Moderate acne: 20-100 comedones, or 15-50 inflammatory lesions or a total lesion count of 30-125 c. Severe acne: more than 5 cysts, or comedone count greater than 100, or a total inflammatory count greater than 50, or a total lesion count greater than 125 2. Male and female patients aged between 18 to 30 years. 3. Subjects willing to comply with study visits and procedure 4. Patients taking certain topical and systemic treatments required to undergo 01 month washout periods before they can enter the study.
Exclusion criteria
Exclusion criteria: 1. Patients not willing to sign consent form 2. Who have a diagnosed hormonal or endocrine cause for acne 3. Acne conglobata, acne fulminans, secondary acne, severe acne, or other dermatologic conditions requiring systemic treatment. 4. Women are to be excluded if they are pregnant, planning a pregnancy or nursing 5. Patients having any contraindication to clindamycin or adapalene 6. Men with beards are excluded if these are likely to cause interference with study assessments 7. Any significant medical condition which may interfere with the patients optimal participation in the study as per Investigators opinion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the effectiveness of hydro swelling polymer delivery system with microsphere delivery system of a combination of adapalene 0.1% + clindamycin 1% in patients with acne.Timepoint: day 0, day 28, day 56 | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the safety of hydro swelling polymer delivery system with microsphere delivery system of a combination of adapalene 0.1% & clindamycin 1% in patients with acneTimepoint: Day 0, day 28, Day 56 | — |
Countries
India
Contacts
Public ContactDr Shrilata S Trasi
Outcome results
None listed