A clinical trial to study the effect of brushing with 3 different commercial toothpastes on oral health

Effectiveness of three commercially available dentifrices of different medicinal systems on gingivitis, salivary pH and Mutans Streptococci count: A randomized controlled double blinded concurrent parallel study.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/04/013103

Enrollment

Registered

2018-04-09

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- mild to moderate gingivitis

Interventions

Intervention1: commercially available dentifrice with one of the active ingredient as fluoride : brushing twice daily for 2 minutes using commercially available dentifrice with one

Eligibility

Inclusion criteria

Inclusion criteria: Subjects with informed or written consent,Subjects having Gingival Index (GI) mean > 1.0, Presence of at least 20 natural permanent teeth.

Exclusion criteria

Exclusion criteria: Individuals under antimicrobial therapy at least 1 month prior to the study and using mouth rinses or dentifrices containing substances with anti-inflammatory properties, Subjects who are medically compromised, Patient with intra oral appliance or dentures

Design outcomes

Primary

Measure	Time frame
Reduction in gingival index score and reduction in modified plaque index scoreTimepoint: 15,30,45,60 days	—

Secondary

Measure	Time frame
Increase in salivary pHTimepoint: 15,30,45,60 days;Reduction in Salivary Mutans Streptococci countsTimepoint: 15,30,45,60 days	—

Countries

India

Contacts

Public ContactDr Manumanthu V Ramesh

Faculty of Dental Sciences IMS, Banaras Hindu University

pgnaveenkumar@gmail.com9482562631

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026